Tuesday, December 10, 2019

These Gut Bacteria Brew Their Own Booze, and May Harm Livers in People Who Don't Drink

From Live Science.com (Sept. 19):

It's common knowledge that drinking too much alcohol can lay waste to your liver. But now, researchers have spotted a strain of gut bacteria that produces its own booze in copious amounts — high enough to potentially pose a risk of liver problems in people who don't drink at all.

Although much more research is needed to confirm the results, they suggest that these boozy bacteria may contribute to nonalcoholic fatty liver disease (NAFLD), a condition in which fat builds up in the liver for reasons unrelated to alcohol consumption.

The researchers first stumbled upon this unusual microbe while they were studying a patient with a curious condition: The patient had so-called auto-brewery syndrome (ABS), an extremely rare condition that leaves people drunk after eating sugary food. In the week before he sought medical care, the unfortunate patient became inebriated each time he consumed a carbohydrate-rich meal and his blood-alcohol concentration had occasionally spiked to potentially lethal levels, around 0.4%. He was even suspected to be a "closet drinker" by his friends, according to the new study, published today (Sept. 19) in the journal Cell Metabolism.

ABS has been linked to yeast infections, wherein the fungus ferments alcohol in the intestines just as it brews beer in barrels; but in this case, yeast wasn't the culprit. [read more]

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